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Recombinant viruses as vaccines against viral diseases BJMBR
Souza,A.P.D.; Haut,L.; Reyes-Sandoval,A.; Pinto,A.R..
Vaccine approaches to infectious diseases are widely applied and appreciated. Amongst them, vectors based on recombinant viruses have shown great promise and play an important role in the development of new vaccines. Many viruses have been investigated for their ability to express proteins from foreign pathogens and induce specific immunological responses against these antigens in vivo. Generally, gene-based vaccines can stimulate potent humoral and cellular immune responses and viral vectors might be an effective strategy for both the delivery of antigen-encoding genes and the facilitation and enhancement of antigen presentation. In order to be utilized as a vaccine carrier, the ideal viral vector should be safe and enable efficient presentation of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Vaccine; Immunity; Recombinant viruses; Viral vectors; Infectious disease.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000400004
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